Abstract

Medication-related osteonecrosis of the jaws (MRONJ) is a pathology related to invasive dental procedures or an inflammatory process unrelated to invasive dental procedures. This review aimed to answer the research question: What are the preventive methods for medication-related osteonecrosis of the jaw in Implant Dentistry? This scoping review was conducted following the Joanna Briggs Institute method, PRISMA extension for Scoping Reviews (PRISMA-ScR). An electronic literature search was conducted up to April 2024 in MEDLINE/PubMed, Scopus, LILACS, Web of Science, and Embase. The grey literature screening was done in OpenGrey, Google Scholar, and ProQuest, and a qualitative analysis was conducted. Out of 3800 studies identified, 26 were included (15 case reports, three case series, five retrospectives, three prospective). Eleven studies reported MRONJ cases. The preventive method reported were: antiresorptive/antiangiogenic medication suspension (n = 17), antibiotic prophylaxis (n = 22), CTX test (n = 10), plasma rich on factor growth (PRGF) (n = 3), platelet rich in fibrin (PRF) (n = 1), antimicrobial dynamic phototherapy (a-PDT) (n = 2), diode laser (n = 1), and ozone therapy (n = 1). Preventive strategies for MRONJ in Implant Dentistry remain inconclusive. However, a-PDT and PRGF have shown potential as promising methods.