Editorial Type:
Article Category: Research Article
 | 
Online Publication Date: 01 Aug 2019

Randomized Controlled Trials in Implant Dentistry: Assessment of the Last 20 Years of Contribution and Research Network Analysis

PhD,
PhD,
PhD, and
PhD
Page Range: 327 – 333
DOI: 10.1563/aaid-joi-D-18-00276
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The aim of this study was to evaluate the characteristics of randomized controlled trials (RCTs) regarding implant-supported single tooth or fixed partial dentures. We performed searches (PubMed/MEDLINE and Web of Science) to identify all RCTs published from 1996 to 2016 and assessed publication details, study characteristics, international collaboration networks, and characteristics related to the implant-supported treatment. Two reviewers independently screened the titles/abstracts and selected full texts. A total of 122 RCTs were included, and most of the authors were from Europe (72%). Most trials did not report a trial registering number (89.9%) or sample size calculation (58.2%). The use of the CONSORT Statement increased over the past 9 years. Trials were mostly conducted at universities (54.9%), and only 13.1% compared 2 or more implant brands. Loading protocol was the most prevalent main comparison among the included studies, and most of the RCTs did not clearly report whether they excluded patients with known risk factors. The studies reviewed here presented different methodological and publication characteristics, and many did not show aspects aligned with current research practices.

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Figure 1

Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) flowchart.10


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Figure 2

Randomized controlled trial distribution according to journals.


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Figure 3

Randomized controlled trial distribution according to countries and continents.


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Figure 4

Authors' country of affiliation social network. Only countries with 3 or more collaborations are presented in the network (connected with lines). The sizes of the vertices (countries) are proportional to the number of authors accounted for each country (number below the countries' names). The number that appears in the lines corresponds to the number of international collaborations between different countries.


Contributor Notes

Corresponding author, e-mail: mateusbertolini@yahoo.com.br
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