Diffuse Large B-Cell Lymphoma of the Peri-Implant Mucosa Mimicking Peri-Implantitis

Histopathology and immunohistochemical staining of biopsy from neck lymph node. (a) Effacement of nodal architecture with diffuse infiltration of large atypical lymphoid cells (hematoxylin and eosinc; original magnification, ×200 and ×400). Tumor cells were positive for CD20 (b), Bcl-2 (c), and MUM-1 (d), but negative for CD10 (e). Original magnification, ×200, each.

(a) Clinical view indicating bleeding on probing and suppuration were observed at first visit. (b) Periapical radiograph indicating alveolar bone loss around the dental implant.

Histopathology and immunohistochemical staining of biopsy from peri-implant mucosa. (a) Diffuse infiltration of large atypical lymphoid cells (hematoxylin and eosin; original magnification, ×200 and ×400). Tumor cells were positive for CD20 (b) but negative for CD3(c). Original magnification, ×200, each.
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