Editorial Type:
Article Category: Other
 | 
Online Publication Date: 01 Jun 2015

Current Approaches of Bone Morphogenetic Proteins in Dentistry

DDS,
PhD, DDS,
DDS,
DDS,
PhD, DDS, and
PhD, DDS, MSc
Page Range: 337 – 342
DOI: 10.1563/AAID-JOI-D-13-00012
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Bone morphogenic proteins (BMPs) are a group of osteoinductive proteins obtained from nonmineralized bone matrix; they are capable of stimulating the differentiation of pluripotent mesenchymal cells to osteoprogenitor cells. They have become a likely treatment option, given their action on regeneration and remodeling of bone lesions and increasing the bone response around alloplastic materials. It may be feasible in the near future for BMPs to replace autologous and allogenic bone grafts. The application of specific growth factors for osteoinduction without using a bone graft constitutes a real impact on bone regeneration. The use of BMP is not only focused on osteogenic regeneration: There are a variety of studies investigating other properties, such as periodontal or dental regeneration from the conservative viewpoint. In this review, we will highlight the role of the BMP in bone, periodontal and dental regeneration.

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Figure 1.

BMP investigations in dentistry published during the last five years exploring the Medline database (http://www.ncbi.nim.nih.gov) in the following areas: bone regeneration;915,17,1825,27,4447 dental regeneration;3840,42,43,50; periodontal regeneration.4,2937,51


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Figure 2.

Type of BMP investigated in dentistry researches published during the last five years exploring the Medline database (http://www.ncbi.nim.nih.gov). Areas: bone regeneration;915,17,1825,27,4447 dental regeneration;3840,42,43,50 periodontal regeneration.4,2937,51


Contributor Notes

Corresponding author, e-mail: danieltl@us.es
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