Peripheral Giant Cell Granuloma Associated With Dental Implants: Clinical Case and Literature Review
Peripheral giant cell granuloma (PGCG) associated to dental implants is a very infrequent peri-implant soft-tissue complication, with only 11 cases recorded in the literature to date. The present study describes a 54-year-old woman presenting a swelling of the alveolar margin in the fourth quadrant in relation to a fixed prosthesis cemented over implants. Treatment consisted of complete resection of the lesion with implantoplasty of the exposed implant threads. The diagnosis of PGCG was confirmed by histological study, and no relapse has been recorded after 12 months of follow-up.
Figure 1. Intraoral exploration revealed an elastic, exophytic, and nonulcerated lesion located between 2 implants in the right lower region. Figure 2. Radiograph showing horizontal bone loss. Measurement was made using the Cliniview version 5.1 program.
Intraoral view. (a, b) The intraoral image shows the removal of the lesion and polishing the implant threads. (c) Adequate healing of the zone was confirmed 7 days after the lesion was removed.
Figure 4. (a) Low magnification (×2.5) showing ulceration of the mucosa of the fibrohistiocytic stroma and numerous giant cells. (b) Medium magnification (×10) revealed abundant multinucleated giant cells together with histiocytic cells, blood capillaries, and hemorrhagic foci. Figure 5. (a) Clinical photograph taken 1 year after the removal of the lesion. Satisfactory soft-tissue healing took place, and the lesion did not recur. (b) Follow-up radiograph demonstrating a stable bone level.
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