Human Histologic Analysis of Mineralized Bone Allograft (Puros) Placement Before Implant Surgery
Because clinicians are placing more dental implants, it is becoming more important to maintain bone volume after tooth extraction. This article discusses the various bone-augmentation materials available to the clinician and illustrates a case report of particulate mineralized bone allograft (Puros) placement after extraction. Exposure of the grafted site after 5 months revealed a hard bony structure. Human histologic analysis at the light microscopic level revealed nonvital spicules of mature calcified bone having a highly organized matrix surrounded by viable noncalcified immature bone matrix, or osteoid. It was concluded that mineralized human allograft demonstrated the formation or remodeling of bone histologically and was clinically useful to maintain bone volume for implant placement after extraction. To the authors' knowledge, this is the first publication to demonstrate human histology of particulate mineralized bone allograft (Puros) after placement into an extraction site.Abstract

The patient's lower-right second molar exhibits a large radiolucency. Periodontal probing indicated a endodontic-periodontic lesion with a hopeless prognosis


Contributor Notes
John C. Minichetti, DMD, is in private practice in Englewood, NJ, attending Englewood Hospital. Address correspondence to Dr Minichetti at 370 Grand Avenue, Englewood, NJ 07631 (Dminichett@aol.com).
Joseph C. D'Amore, DDS, is in private practice in Englewood, NJ.
Anna Y. J. Hong, DDS, is a clinical instructor at the Dental Hygiene School, Bergen County College, Paramus, NJ, and in private practice in Englewood, NJ.
Deborah B. Cleveland, DDS, is an associate professor of Oral Pathology at the New Jersey Dental School, University of Medicine and Dentistry, Newark, NJ.